Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963613 | 0.86 | DHFR (0.38) | ALDH1A1KDM4EPOLBCYP1A2ALOX15 | |
| SCHEMBL12971340 | 0.78 | NOS2 (0.35) | ALDH1A1KDM4EIKBKBCYP1A2ALOX15 | |
| SCHEMBL2317715 | 0.78 | NOS2 (0.35) | ALDH1A1KDM4EIKBKBNOS2NOS3 | |
| SCHEMBL28211073 | 0.78 | TYR (0.41) | ALDH1A1KDM4EALOX15CASP7HSD17B10 | |
| SCHEMBL11148575 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBALOX15NOS2 | |
| SCHEMBL9690320 | 0.74 | NOS2 (0.33) | ALDH1A1KDM4EPOLBNOS2NOS3 | |
| SCHEMBL150659 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EPOLBCYP1A2ALOX15 | |
| SCHEMBL840292 | 0.74 | NOS2 (0.33) | ALDH1A1KDM4EIKBKBCYP1A2ALOX15 | |
| SCHEMBL29488043 | 0.74 | ALDH1A1 (0.37) | ALDH1A1KDM4EPOLBCYP1A2ALOX15 | |
| SCHEMBL15270 | 0.74 | ALDH1A1 (0.37) | ALDH1A1KDM4EPOLBCYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705863-A1 | Two stage melt polymerization process for making polybenzimidazoles | HOECHST CELANESE CORPORATION (US) | 1996-04-10 | — | — | EP | disclosed |
| US-4895928-A | AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4717764-A | Two stage melt polymerization process for making polymers containing aromatic amide groups | CELANESE CORPORATION (US) | 1988-01-05 | — | — | US | disclosed |