Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975796 | 0.81 | DDB1 (0.34) | MAPTDDB1CRBNCDC7CTSB | |
| SCHEMBL27154384 | 0.76 | CDC7 (0.33) | DDB1CRBNCDC7CTSB | |
| SCHEMBL29643693 | 0.76 | CDC7 (0.33) | DDB1CRBNCDC7CTSB | |
| SCHEMBL8976113 | 0.74 | CYP1A2 (0.40) | CYP1A2MCL1EGFRSRCMAPT | |
| SCHEMBL1921514 | 0.72 | MAPT (0.46) | CYP1A2MCL1EGFRSRCMAPT | |
| SCHEMBL8976235 | 0.70 | FEN1 (0.42) | CYP1A2EGFRSRCMAPTDDB1 | |
| SCHEMBL29202644 | 0.70 | KDM4E (0.52) | EGFRSRCMAPTGAAMAPK1 | |
| SCHEMBL29311431 | 0.69 | PDE3B (0.44) | CYP1A2MAPK1HTTNPSR1CDC7 | |
| SCHEMBL9979912 | 0.69 | MAPT (0.43) | CYP1A2MCL1EGFRSRCMAPT | |
| SCHEMBL29989268 | 0.68 | EGFR (0.38) | CYP1A2MCL1EGFRSRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532261-A | TREATING STAPHYLOCOCCUS INFECTIONS | MERCK & CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |