Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976353 | 0.81 | KDM4E (0.33) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8975820 | 0.74 | CYP1A2 (0.38) | CYP1A2MAPTPOLBMCL1HTT | |
| SCHEMBL1921514 | 0.72 | MAPT (0.46) | CYP1A2MAPTMCL1HTTEGFR | |
| SCHEMBL8976235 | 0.70 | FEN1 (0.42) | CYP1A2MAPTHTTEGFRSRC | |
| SCHEMBL29202644 | 0.70 | KDM4E (0.52) | MAPTHTTLMNANPSR1EGFR | |
| SCHEMBL9979912 | 0.69 | MAPT (0.43) | CYP1A2MAPTMCL1HTTEGFR | |
| SCHEMBL14744699 | 0.67 | MAPT (0.39) | CYP1A2MAPTPOLBMCL1LMNA | |
| SCHEMBL27240229 | 0.66 | ALDH1A1 (0.47) | CYP1A2MAPTMCL1HTTLMNA | |
| SCHEMBL1929490 | 0.66 | ACHE (0.51) | CYP1A2MAPTMCL1EGFRSRC | |
| SCHEMBL14479468 | 0.66 | MAPK8 (0.48) | CYP1A2MCL1LMNAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532261-A | TREATING STAPHYLOCOCCUS INFECTIONS | MERCK & CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |