Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921514 | 0.95 | MAPT (0.46) | MAPTMCL1ACHEDNM1SMN1; SMN2 | |
| SCHEMBL12418696 | 0.90 | GPR3 (0.59) | MAPTACHEGPR3KDM4EALDH1A1 | |
| SCHEMBL5014769 | 0.86 | ACHE (0.41) | MAPTMCL1ACHEDNM1SMN1; SMN2 | |
| SCHEMBL1923381 | 0.85 | GPR3 (0.64) | MAPTACHEGPR3KDM4EALDH1A1 | |
| SCHEMBL5532447 | 0.85 | ACHE (0.47) | MAPTMCL1ACHEDNM1SMN1; SMN2 | |
| SCHEMBL10871998 | 0.84 | MAPT (0.45) | MAPTMCL1ACHEDNM1SMN1; SMN2 | |
| SCHEMBL1929490 | 0.83 | ACHE (0.51) | MAPTMCL1ACHEDNM1SMN1; SMN2 | |
| SCHEMBL14479468 | 0.83 | MAPK8 (0.48) | MCL1ACHEALDH1A1MEN1KMT2A | |
| SCHEMBL12418698 | 0.82 | GPR3 (0.59) | MAPTACHESMN1; SMN2GPR3KDM4E | |
| SCHEMBL3281839 | 0.81 | GPR3 (0.44) | MAPTMCL1ACHESMN1; SMN2GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-8110690-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2012-02-07 | — | — | US | disclosed |
| US-8003807-B2 | organic thin film transistor with a semiconductor layer including the small molecule having didodecylindolo[3,2-b]carbazole groups | XEROX CORPORATION (US) | 2011-08-23 | — | — | US | disclosed |
| US-7868186-B2 | Device containing polymer having indolocarbazole- repeat unit and divalent linkage | XEROX CORPORATION (US) | 2011-01-11 | — | — | US | disclosed |
| US-7829727-B2 | Device containing compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION (US) | 2010-11-09 | — | — | US | disclosed |
| US-20100230670-A1 | DEVICE CONTAINING COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | XEROX CORPORATION (US) | 2010-09-16 | — | — | US | disclosed |
| US-20090114909-A1 | organic thin film transistor with a semiconductor layer including the polymer of 2,8-Bis(2-thienyl)-5,11-didodecylindolo[3,2-b]carbazole; organic photovoltaics | XEROX CORPORATION (US) | 2009-05-07 | — | — | US | disclosed |
| US-7528261-B2 | Small molecule compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION (US) | 2009-05-05 | — | — | US | disclosed |
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |
| US-7456424-B2 | Thin film transistors including indolocarbozoles | XEROX CORPORATION (US) | 2008-11-25 | — | — | US | disclosed |
| US-20080207917-A1 | POLYMER HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | XEROX CORPORATION (US) | 2008-08-28 | — | — | US | disclosed |
| US-7402681-B2 | Compound with indolocarbazole moieties and devices containing such compound | XEROX CORPORATION (US) | 2008-07-22 | — | — | US | disclosed |
| US-7396852-B2 | Compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION (US) | 2008-07-08 | — | — | US | disclosed |
| US-20080103314-A1 | SMALL MOLECULE COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | XEROX CORPORATION (US) | 2008-05-01 | — | — | US | disclosed |
| US-20070112167-A1 | Device containing compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION | 2007-05-17 | — | — | US | disclosed |
| US-20070112172-A1 | Compound having indolocarbazole moiety and divalent linkage | XEROX CORPORATION | 2007-05-17 | — | — | US | disclosed |
| US-7173140-B2 | Process to form compound with indolocarbazole moieties | XEROX CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | MAPT 196/4885MCL1 814/4885ACHE 1664/4885 |
| US-20070112172-A1 | Compound having indolocarbazole moiety and divalent linkage | INMT, IDO2, GRIN2C | MAPT 163/4885MCL1 964/4885ACHE 360/4885 |
| US-20080103314-A1 | SMALL MOLECULE COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | SLC43A1, SLC7A5, KCNN2 | MAPT 153/4885MCL1 2883/4885ACHE 1858/4885 |
| US-20100230670-A1 | DEVICE CONTAINING COMPOUND HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | BRD4, BICRA, INMT | MAPT 955/4885MCL1 2401/4885ACHE 152/4885 |
| US-20080207917-A1 | POLYMER HAVING INDOLOCARBAZOLE MOIETY AND DIVALENT LINKAGE | SGTA, MTCL3, SMC3 | MAPT 196/4885MCL1 1632/4885ACHE 2677/4885 |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | MAPT 196/4885MCL1 814/4885ACHE 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.