Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975820 | 0.81 | CYP1A2 (0.38) | DDB1CRBNCDC7CTSBMEN1 | |
| SCHEMBL8975764 | 0.71 | FEN1 (0.40) | MEN1KMT2ANR1I2AHRHCRTR1 | |
| SCHEMBL27154384 | 0.68 | CDC7 (0.33) | DDB1CRBNCDC7CTSBPIM1 | |
| SCHEMBL29643693 | 0.68 | CDC7 (0.33) | DDB1CRBNCDC7CTSBPIM1 | |
| SCHEMBL29311431 | 0.67 | PDE3B (0.44) | CDC7KDM4E | |
| SCHEMBL8975983 | 0.65 | MAOA (0.43) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8976111 | 0.64 | ADORA3 (0.43) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9301241 | 0.64 | USP8 (0.41) | NQO1 | |
| SCHEMBL20116584 | 0.62 | ADORA2A (0.37) | DDB1CRBNCDC7CTSBKDM4E | |
| SCHEMBL19231460 | 0.62 | CDC7 (0.44) | DDB1CRBNCDC7PIM1NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532261-A | TREATING STAPHYLOCOCCUS INFECTIONS | MERCK & CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |