SCHEMBL8976133

SCHEMBL8976133

Cc1c(OC(=O)O)c(O)cc2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.40
MEN1 O00255 10/20 0.40
KMT2A Q03164 10/20 0.40
KDM4E B2RXH2 8/20 0.40
USP2 O75604 6/20 0.40
RECQL P46063 6/20 0.40
ALDH1A1 P00352 6/20 0.40
MAPK1 P28482 5/20 0.40
THRB P10828 5/20 0.40
CYP3A4 P08684 5/20 0.40
TDP1 Q9NUW8 5/20 0.40
HPGD P15428 4/20 0.40
HSD17B10 Q99714 3/20 0.40
BRCA1 P38398 3/20 0.40
PIM1 P11309 2/20 0.40
MAOA P21397 2/20 0.40
TP53 P04637 2/20 0.40
ALOX15 P16050 2/20 0.40
CSNK2A2 P19784 2/20 0.40
CSNK2B P67870 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8976204 0.77 MEN1 (0.49) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL5305956 0.74 MAPT (0.45) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL8976457 0.73 MAPT (0.55) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL23198971 0.73 MEN1 (0.58) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL4455117 0.71 MEN1 (0.50) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL4460906 0.70 BCL2 (0.44) MAPTMEN1KMT2AKDM4ERECQL
SCHEMBL29066464 0.70 MAPT (0.63) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL5301792 0.69 MAPT (0.48) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL5309173 0.69 PIM1 (0.47) MAPTMEN1KMT2AKDM4EUSP2
SCHEMBL5308050 0.68 MAPT (0.61) MAPTMEN1KMT2AKDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP claimed