SCHEMBL897627

SCHEMBL897627

N#Cc1cccc(NN)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.61
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
KCNA5 P22460 1/20 0.50
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.46
GRM4 Q14833 1/20 0.45
GAA P10253 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HSD17B10 Q99714 2/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
PDK1 Q15118 1/20 0.44
PDK2 Q15119 1/20 0.44
PDK3 Q15120 1/20 0.44
PDK4 Q16654 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP7 P55210 1/20 0.44
ENPP2 Q13822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29574760 1.00 IDO1 (0.61) IDO1ALDH1A1MAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL29825818 0.98 IDO1 (0.59) IDO1ALDH1A1MAPTKMT2AMEN1
Bromide SCHEMBL20984393 0.98 IDO1 (0.59) IDO1ALDH1A1MAPTKMT2AMEN1
Hydrochloric Acid SCHEMBL1765443 0.98 IDO1 (0.59) IDO1ALDH1A1MAPTKMT2AMEN1
Oxalic Acid SCHEMBL20984276 0.89 MAPT (0.55) IDO1ALDH1A1MAPTKMT2AMEN1
Sulfuric Acid SCHEMBL20984342 0.89 IDO1 (0.55) IDO1ALDH1A1MAPTKMT2AMEN1
Phosphoric Acid SCHEMBL20984312 0.89 IDO1 (0.55) IDO1ALDH1A1MAPTKMT2AMEN1
Oxalic Acid SCHEMBL20984274 0.89 MAPT (0.55) IDO1ALDH1A1MAPTKMT2AMEN1
Nitric Acid SCHEMBL20984285 0.86 IDO1 (0.53) IDO1ALDH1A1MAPTKMT2AMEN1
SCHEMBL953597 0.82 ALDH1A1 (0.56) IDO1ALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119909085-A Application of pyruvate in preparation of medicines for treating pulmonary biofilm infection 江苏长泰药业股份有限公司 2025-05-02 CN claimed
CN-106928184-B A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德药业有限公司 2019-09-20 CN claimed
CN-106928185-B A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德药业有限公司 2019-09-20 CN claimed
CN-105777710-B A kind of Ai Le replaces the synthetic method of Buddhist nun 湖南欧亚药业有限公司 2018-09-04 CN claimed
CN-107129488-A A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德生物医药技术开发有限公司 2017-09-05 CN claimed
CN-106995433-A A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德生物医药技术开发有限公司 2017-08-01 CN claimed
CN-106928185-A A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德生物医药技术开发有限公司 2017-07-07 CN claimed
CN-106928184-A A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德生物医药技术开发有限公司 2017-07-07 CN claimed
CN-105777710-A Synthesis method of Alectinib 湖南欧亚生物有限公司 2016-07-20 CN claimed
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TERRAN BIOSCIENCES INC (US) 2026-05-21 US disclosed
US-RE50878-E1 Pyrazolo pyridine derivatives as NADPH oxidase inhibitors CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2026-05-05 US disclosed
CN-119909085-A Application of pyruvate in preparation of medicines for treating pulmonary biofilm infection 江苏长泰药业股份有限公司 2025-05-02 CN disclosed
US-20250114327-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-04-10 US disclosed
EP-4423088-A2 AZEPINO-INDOLES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS Terran Biosciences, Inc. (US) 2024-09-04 EP disclosed
US-5869516-A 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-02-09 US disclosed
US-5852030-A Indole derivatives, process for producing the same and medicinal uses of the same TORAY INDUSTRIES, INC. (JP) 1998-12-22 US disclosed
WO-1998028269-A1 NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS DU PONT PHARMACEUTICALS COMPANY (US) 1998-07-02 WO disclosed
CN-1141291-A 4-(Arylaminomethylene)-2,4-dihydro-3-pyrazolones MERCK PATENT GMBH (DE) 1997-01-29 CN disclosed
EP-0743304-A1 4-(Arylaminomethylene)-2,4-dihydro-pyrazol-3-ones MERCK PATENT GmbH (DE) 1996-11-20 EP disclosed
EP-0614898-A1 INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 1994-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138985-A1 Azepino-Indoles for the Treatment of Neurological and Psychiatric Disorders TPH2, TPH1, HTR1D IDO1 20/4885ALDH1A1 1332/4885MAPT 1145/4885
US-20250114327-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND ALK, ALPI, TTR IDO1 1495/4885ALDH1A1 308/4885MAPT 240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.