Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960048 | 0.83 | NPFFR2 (0.36) | TSHRALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31226955 | 0.81 | TSHR (0.43) | MAPTRAB9ANPC1TSHRPKM | |
| SCHEMBL9212477 | 0.81 | TSHR (0.65) | MAPTTSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL8478583 | 0.80 | TSHR (0.64) | MAPTRAB9ANPC1TSHRPKM | |
| SCHEMBL313211 | 0.80 | TSHR (0.64) | MAPTRAB9ANPC1TSHRPKM | |
| SCHEMBL29655535 | 0.80 | TSHR (0.64) | MAPTRAB9ANPC1TSHRPKM | |
| SCHEMBL3033312 | 0.80 | MAPT (0.47) | MAPTRAB9ANPC1CYP2A6PKM | |
| SCHEMBL1528984 | 0.79 | ALDH1A1 (0.54) | MAPTRAB9ANPC1TSHRKDM4E | |
| SCHEMBL703716 | 0.77 | HPGD (0.53) | RAB9ANPC1CYP2A6ALDH1A1KMT2A | |
| SCHEMBL22325351 | 0.77 | PKM (0.50) | MAPTRAB9ANPC1CYP2A6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500418-A | ANTIEPILEPTIC | CIBA-GEIGY CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| US-5376684-A | Aminobutyric acid antagonist; antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |