Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305755 | 0.93 | LTA4H (0.52) | LTA4HKIF11KCNH2TAAR1SLC6A2 | |
| Maleic Acid SCHEMBL8867414 | 0.89 | ALDH1A1 (0.48) | KMT2AKIF11TAAR1MMP1MMP13 | |
| Fumaric Acid SCHEMBL8867443 | 0.89 | ALDH1A1 (0.48) | KMT2AKIF11TAAR1MMP1MMP13 | |
| SCHEMBL17964411 | 0.86 | LTA4H (0.55) | LTA4HKMT2AKIF11KCNH2TAAR1 | |
| SCHEMBL855070 | 0.83 | TAAR1 (0.64) | KIF11TAAR1SLC6A2LMNASMN1; SMN2 | |
| Fumaric Acid SCHEMBL8866060 | 0.82 | MMP1 (0.47) | KMT2AKIF11TAAR1SLC6A2MMP1 | |
| Maleic Acid SCHEMBL8866047 | 0.82 | MMP1 (0.47) | KMT2AKIF11TAAR1SLC6A2MMP1 | |
| SCHEMBL2671508 | 0.82 | LTA4H (0.60) | LTA4HKMT2ATAAR1SLC6A2CASR | |
| SCHEMBL5308325 | 0.82 | KIF11 (0.50) | KIF11TAAR1SLC6A2CASRSIGMAR1 | |
| SCHEMBL8865724 | 0.82 | MAOB (0.57) | LTA4HSLC6A2L3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539120-A | Arylalkyl-amines having anticonvulsant and neuroprotective properties | AGENCE SPATIALE EUROPEENNE (FR) | 1996-07-23 | — | — | US | claimed |
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | claimed |
| EP-0356035-A2 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1990-02-28 | — | — | EP | claimed |