Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.43 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976751 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976956 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976961 | 0.81 | ALDH1A1 (0.55) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976340 | 0.79 | SMN1; SMN2 (0.68) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976337 | 0.79 | SMN1; SMN2 (0.68) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976331 | 0.72 | SMN1; SMN2 (0.62) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976338 | 0.72 | SMN1; SMN2 (0.62) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976310 | 0.72 | SMN1; SMN2 (0.62) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976303 | 0.72 | SMN1; SMN2 (0.62) | ALDH1A1LMNAUSP2ALOX15MAPK1 | |
| SCHEMBL8976618 | 0.72 | SIGMAR1 (0.64) | ALDH1A1LMNAUSP2ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707004-A1 | 1-Arylalcenyl 4-arylmethylpiperazinderivatives, process for their preparation and pharmaceutical composition containing them | ADIR ET COMPAGNIE (FR) | 1996-04-17 | — | — | EP | disclosed |