Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.30 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614628 | 0.98 | PLA2G2A (0.38) | PLA2G2APLA2G5PLA2G10PSMB5MEN1 | |
| SCHEMBL6830439 | 0.79 | MEN1 (0.42) | MEN1FAAHMAPK1KMT2AMMP8 | |
| SCHEMBL8614630 | 0.75 | PLA2G2A (0.38) | PLA2G2APLA2G5PLA2G10PSMB5MEN1 | |
| SCHEMBL965005 | 0.74 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL7684377 | 0.72 | EPHX1 (0.47) | FAAHEPHX1 | |
| SCHEMBL29055799 | 0.72 | FAAH (0.44) | FAAHEPHX1 | |
| SCHEMBL1400991 | 0.69 | AKR1B1 (0.39) | MEN1KMT2A | |
| SCHEMBL7674452 | 0.69 | FAAH (0.50) | FAAHKMT2A | |
| SCHEMBL10925540 | 0.68 | DNM1 (0.39) | MEN1KMT2A | |
| SCHEMBL7686630 | 0.68 | CES2 (0.34) | MEN1FAAHKMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706532-A1 | NEW COMPOUND AND ITS PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |