Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101786 | 0.96 | MGLL (0.46) | KDM4ESMN1; SMN2NPC1RAB9APTGS1 | |
| SCHEMBL8652814 | 0.94 | MGLL (0.47) | KDM4ESMN1; SMN2NPC1RAB9APTGS1 | |
| SCHEMBL5570285 | 0.92 | MGLL (0.50) | KDM4EPTGS1PTGS2MGLLFAAH | |
| SCHEMBL11868886 | 0.90 | KDM4E (0.43) | KDM4ESMN1; SMN2NPC1RAB9APTGS1 | |
| SCHEMBL3142849 | 0.88 | KDM4E (0.42) | KDM4ESMN1; SMN2NPC1RAB9APTGS1 | |
| SCHEMBL3142469 | 0.88 | MGLL (0.40) | KDM4ESMN1; SMN2NPC1RAB9APTGS1 | |
| SCHEMBL6162730 | 0.87 | MAPT (0.35) | KDM4ESMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL3420629 | 0.83 | MAPT (0.49) | KDM4ESMN1; SMN2PTGS1PTGS2MGLL | |
| SCHEMBL9466598 | 0.81 | KDM4E (0.51) | KDM4ESMN1; SMN2PTGS1PTGS2MGLL | |
| SCHEMBL9432000 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610126-B1 | A system for determining the electrical potential across a membrane | UNIV CALIFORNIA (US) | 2014-04-30 | — | — | EP | disclosed |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| EP-1409456-B1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | UNIV CALIFORNIA (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-0977035-B2 | A system for determining the electrical potential across a membrane | UNIV CALIFORNIA (US) | 2010-07-21 | — | — | EP | disclosed |
| US-7687282-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-30 | — | — | US | disclosed |
| EP-1688466-B1 | Ink composition, ink jet recording method, printed material, method of producing planographic printing plate, and planographic printing plate | FUJIFILM CORP (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| US-20070259903-A1 | ANTI-VIRAL USES FOR ANALOGS OF BARBITURIC ACID | GULLIYA KIRPAL S | 2007-11-08 | — | — | US | disclosed |
| US-7173130-B2 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-06 | — | — | US | disclosed |
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-01 | — | — | US | disclosed |
| EP-0977035-A2 | A system for determining the electrical potential across a membrane | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0834074-B1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | UNIV CALIFORNIA (US) | 1999-11-03 | — | — | EP | disclosed |
| US-5869494-A | ADMINISTERING AS ANTITUMOR AGENTS, IMMUNE SYSTEM MODULATORS AND ANTIDEPRESSANTS | GULLIYA KIRPAL S (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0834074-A1 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5674870-A | Anti-cancer uses for barbituric acid analogs | GULLIYA KIRPAL S (US) | 1997-10-07 | — | — | US | disclosed |
| US-5661035-A | Voltage sensing by fluorescence resonance energy transfer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996041166-A2 | DETECTION OF TRANSMEMBRANE POTENTIALS BY OPTICAL METHODS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0591786-B1 | Photosensitive composition | FUJI PHOTO FILM CO LTD (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0591786-A2 | Photosensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-4636459-A | PHOTOINITIATOR AND UNSATURATED MONOMER; PRINTING PLATES | FUJI PHOTO FILM CO., LTD. (JP) | 1987-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259903-A1 | ANTI-VIRAL USES FOR ANALOGS OF BARBITURIC ACID | SARS1, SLC6A1, BAK1 | KDM4E 1150/4885SMN1; SMN2 2131/4885NPC1 1320/4885 |
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | KDM4E 2422/4885SMN1; SMN2 4522/4885NPC1 4051/4885 |
| US-20070026384-A1 | Detection of transmembrane potentials by optical methods | MBOAT1, TRPM4, NME4 | KDM4E 4599/4885SMN1; SMN2 4297/4885NPC1 335/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | KDM4E 2483/4885SMN1; SMN2 4430/4885NPC1 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.