Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977000 | 1.00 | ALDH1A1 (0.48) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL5612605 | 0.83 | LMNA (0.39) | ALDH1A1CHRNB2CHRNA4TSHRTP53 | |
| SCHEMBL9133041 | 0.77 | ESR2 (0.36) | ALDH1A1CHRNB2CHRNA4TSHRTP53 | |
| SCHEMBL126186 | 0.77 | ALDH1A1 (0.58) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9065756 | 0.73 | LMNA (0.38) | ALDH1A1TSHRTP53CYP3A4LMNA | |
| SCHEMBL11136720 | 0.73 | TDP1 (0.48) | ALDH1A1TSHRCYP3A4TDP1MAPT | |
| SCHEMBL3791268 | 0.73 | CYP2A6 (0.38) | ALDH1A1CHRNA7TSHRTP53CYP3A4 | |
| SCHEMBL30046823 | 0.73 | NFE2L2 (0.43) | ALDH1A1TSHRTP53CYP3A4LMNA | |
| SCHEMBL11136726 | 0.73 | TDP1 (0.48) | ALDH1A1TSHRCYP3A4TDP1MAPT | |
| SCHEMBL9216513 | 0.73 | MEN1 (0.46) | ALDH1A1TP53CYP3A4LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6220297-A | — | — | None | — | — | JP | disclosed |
| EP-0490588-B1 | A method of forming high-temperature resistant polymers | LOCTITE IRELAND LTD (IE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0490589-B1 | Styryloxy compounds and polymers thereof | LOCTITE IRELAND LTD (IE) | 1995-03-08 | — | — | EP | disclosed |
| JP-H06220297-A | METHOD OF FORMING HIGH-TEMPERATURE RESISTANT POLYMER | LOCTITE IRELAND LTD | 1994-08-09 | — | — | JP | disclosed |
| US-5141970-A | Photocuring an ether-ring substituted styrene and heating the Claisen-rearranged product to crosslink | LOCTITE (IRELAND) LIMITED (IE) | 1992-08-25 | — | — | US | disclosed |
| EP-0490589-A1 | Styryloxy compounds and polymers thereof | LOCTITE (IRELAND) Ltd. (IE) | 1992-06-17 | — | — | EP | disclosed |
| EP-0490588-A1 | A method of forming high-temperature resistant polymers | LOCTITE (IRELAND) Ltd. (IE) | 1992-06-17 | — | — | EP | disclosed |
| US-5084490-A | Polymers for use in surface coatings, films, inks, adhesives and seals | LOCTITE (IRELAND) LIMITED (IE) | 1992-01-28 | — | — | US | disclosed |