SCHEMBL8977121

SCHEMBL8977121

COc1cc(C(=O)/C=C/c2ccc(O)cc2)ccc1C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 0.69
MAPT P10636 4/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
RAB9A P51151 2/20 0.63
F3 P13726 2/20 0.63
XDH P47989 2/20 0.63
P4HB P07237 1/20 0.63
CALM1 P0DP23 1/20 0.63
ALDH1A1 P00352 1/20 0.63
TNFRSF1A P19438 2/20 0.63
CTSL P07711 1/20 0.62
LMNA P02545 1/20 0.61
ATM Q13315 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
MAOA P21397 2/20 0.60
MAOB P27338 2/20 0.60
CAPN1 P07384 1/20 0.60
PARP1 P09874 1/20 0.60
POLB P06746 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977123 1.00 ABCG2 (0.69) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL8965726 0.92 CA1 (0.70) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL8965729 0.92 CA1 (0.70) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL30383073 0.92 CA1 (0.70) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL8977076 0.89 ABCG2 (0.69) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL8977079 0.89 ABCG2 (0.69) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL8977131 0.89 ABCG2 (0.88) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL8977129 0.89 ABCG2 (0.88) ABCG2MAPTMEN1KMT2ARAB9A
SCHEMBL15807343 0.87 TNFRSF1A (0.79) ABCG2MAPTMEN1KMT2AALDH1A1
SCHEMBL16181228 0.86 ABCG2 (0.86) ABCG2MAPTMEN1KMT2ATNFRSF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP claimed
EP-0428398-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-22 EP claimed
EP-0428398-B1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1996-04-03 EP disclosed
US-5110706-A Photoresists for highly reflective substrates JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-05-05 US disclosed
EP-0428398-A2 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-22 EP disclosed