SCHEMBL8965726

SCHEMBL8965726

COc1cc(C=CC(=O)c2ccc(O)cc2)ccc1C

nearest known ligand 0.80

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.70
CA2 P00918 2/20 0.70
CTSL P07711 2/20 0.70
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
ABCG2 Q9UNQ0 2/20 0.69
CXCL12 P48061 7/20 0.67
CAPN1 P07384 1/20 0.64
CTSB P07858 1/20 0.64
MAPT P10636 3/20 0.63
ALDH1A1 P00352 2/20 0.63
P4HB P07237 1/20 0.63
CALM1 P0DP23 1/20 0.63
RAB9A P51151 1/20 0.63
F3 P13726 1/20 0.63
XDH P47989 1/20 0.63
LMNA P02545 1/20 0.63
TNFRSF1A P19438 1/20 0.63
CXCR4 P61073 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8965729 1.00 CA1 (0.70) CA1CA2CTSLMEN1KMT2A
SCHEMBL30383073 1.00 CA1 (0.70) CA1CA2CTSLMEN1KMT2A
SCHEMBL8977121 0.92 ABCG2 (0.69) CA1CA2CTSLMEN1KMT2A
SCHEMBL8977123 0.92 ABCG2 (0.69) CA1CA2CTSLMEN1KMT2A
SCHEMBL8964940 0.89 CTSL (0.74) CA1CA2CTSLMEN1KMT2A
SCHEMBL8964944 0.89 CTSL (0.74) CA1CA2CTSLMEN1KMT2A
SCHEMBL31233066 0.89 CTSL (0.74) CA1CA2CTSLMEN1KMT2A
SCHEMBL25199646 0.89 ABCG2 (0.88) CA1CA2CTSLMEN1KMT2A
SCHEMBL3440656 0.89 ABCG2 (0.88) CA1CA2CTSLMEN1KMT2A
SCHEMBL3440660 0.89 ABCG2 (0.88) CA1CA2CTSLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-5525457-A Copolymers of unsaturated carboxylic acid, an epoxy-functional monomer, and cinnamoylphenyl group-monomer; high halation preventing effect, involves no sublimation of radiation absorbing components contained therein, possesses excellent heat resistance, dry etching performance, storage stability JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CA1 4078/4885CA2 2635/4885CTSL 357/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CA1 3374/4885CA2 2843/4885CTSL 310/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CA1 3374/4885CA2 2843/4885CTSL 310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.