Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813892 | 0.73 | NR3C1 (0.53) | PTAFRNR3C1PDE4APDE4BPDE4C | |
| SCHEMBL14535309 | 0.72 | LMNA (0.47) | KDM4EGAARAB9ANPSR1PDE4A | |
| SCHEMBL10649598 | 0.72 | ALDH1A1 (0.43) | GAARAB9ANPSR1PTAFRNR3C1 | |
| SCHEMBL22728964 | 0.72 | GID4 (0.68) | GAA | |
| SCHEMBL16654212 | 0.71 | GAA (0.44) | GAARAB9ANPSR1PTAFRNR3C1 | |
| SCHEMBL30633820 | 0.71 | KCNH2 (0.57) | KDM4EPTAFR | |
| SCHEMBL29100531 | 0.71 | KCNH2 (0.57) | KDM4EPTAFR | |
| SCHEMBL7662136 | 0.71 | PDE4A (0.50) | KDM4EGAARAB9ANPSR1PDE4A | |
| SCHEMBL10377232 | 0.70 | — | — | |
| SCHEMBL7453365 | 0.70 | GID4 (0.64) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536853-A | Opiate receptor ligands | CHIRON CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |