Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRND | Q07001 | 1/20 | 0.35 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977393 | 1.00 | KDM1A (0.38) | KDM1ASMN1; SMN2CHRNB2CHRNA4MAPT | |
| SCHEMBL8977326 | 0.82 | MAPT (0.38) | SMN1; SMN2CHRNB2CHRNA4MAPTCHRNA7 | |
| SCHEMBL9049929 | 0.82 | MAPT (0.38) | SMN1; SMN2CHRNB2CHRNA4MAPTCHRNA7 | |
| SCHEMBL9053877 | 0.70 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL14062319 | 0.65 | ACHE (0.49) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28010137 | 0.65 | ALDH1A1 (0.43) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8977392 | 0.65 | CHRNA7 (0.35) | KDM1AMAPTCHRNA7MEN1KMT2A | |
| SCHEMBL5938566 | 0.64 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL5938292 | 0.63 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNA7CHRNA3CHRNB4 | |
| SCHEMBL4825516 | 0.63 | GPR119 (0.43) | CHRNB2CHRNA4CHRNA3CHRNB4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736534-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-10-09 | — | — | EP | disclosed |
| EP-0657456-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1995-06-14 | — | — | EP | disclosed |