Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977322 | 0.79 | HTR2A (0.34) | HTR2AHTR2CC5AR1NCF1HTT | |
| SCHEMBL8977393 | 0.65 | KDM1A (0.38) | CHRNA7KDM1AMAOAMAOBKMT2A | |
| SCHEMBL9050784 | 0.65 | KDM1A (0.38) | CHRNA7KDM1AMAOAMAOBKMT2A | |
| SCHEMBL1621403 | 0.64 | C5AR1 (0.57) | C5AR1HTTKMT2AMEN1ATM | |
| SCHEMBL28010137 | 0.62 | ALDH1A1 (0.43) | HTR2AHTR2CC5AR1KMT2AMEN1 | |
| SCHEMBL19013572 | 0.61 | MEN1 (0.38) | KMT2AMEN1 | |
| SCHEMBL7971332 | 0.60 | GAA (0.50) | HTTKMT2AMEN1LMNAGAA | |
| SCHEMBL14062319 | 0.59 | ACHE (0.49) | HTR2AHTR2CC5AR1KMT2AMEN1 | |
| SCHEMBL11707463 | 0.58 | HTR2A (0.50) | HTR2AHTR2CC5AR1HTTKMT2A | |
| SCHEMBL4402780 | 0.57 | MAPT (0.57) | C5AR1KMT2AMEN1ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545741-A | Process for the preparation of epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-08-13 | — | — | US | disclosed |