SCHEMBL8977522

SCHEMBL8977522

O=C(O)c1cccc(C(F)(F)C(F)(c2cccc(C(=O)O)c2C(=O)O)C(F)(F)F)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 2/20 0.39
FABP4 P15090 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 3/20 0.38
ALDH1A1 P00352 2/20 0.38
ALB P02768 1/20 0.37
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
AKR1C3 P42330 1/20 0.35
PLA2G2D Q9UNK4 1/20 0.35
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
PDK4 Q16654 1/20 0.35
DHODH Q02127 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7095723 0.90 ALOX15 (0.43) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL7096331 0.83 TAS2R14 (0.39) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL17181359 0.82 ALDH1A1 (0.48) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL7091349 0.82 TAS2R14 (0.38) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL7092199 0.82 TAS2R14 (0.38) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL29404866 0.81 TAS2R14 (0.42) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL145576 0.81 TAS2R14 (0.42) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL30269555 0.81 TAS2R14 (0.42) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL9013418 0.80 ALDH1A1 (0.44) TAS2R14FABP4KDM4EHPGDALOX15
SCHEMBL2964734 0.80 TAS2R14 (0.51) TAS2R14FABP4KDM4EHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109863206-A Resin combination, resin sheet, cured film, organic EL display device, semiconductor electronic part, semiconductor devices and organic EL display device manufacturing method 东丽株式会社 2019-06-07 CN disclosed
CN-104662475-B The manufacturing method of positive type photosensitive organic compound, semiconductor devices containing the cured film for having used it 东丽株式会社 2019-03-29 CN disclosed
CN-109313387-A Photosensitive polymer combination 东丽株式会社 2019-02-05 CN disclosed
US-5480965-A BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
EP-0639621-A2 Polyimide-based resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-02-22 EP disclosed
EP-0328027-A2 Novel soluble polyimidesiloxanes and methods for their preparation and use OCCIDENTAL CHEMICAL CORPORATION (US) 1989-08-16 EP disclosed