Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747730 | 0.81 | ALDH1A1 (0.56) | AKR1B1ALDH1A1L3MBTL1PARP1MPL | |
| SCHEMBL22891113 | 0.79 | ALDH1A1 (0.43) | AKR1B1ALDH1A1L3MBTL1PARP1MPL | |
| SCHEMBL24818889 | 0.79 | ALDH1A1 (0.40) | AKR1B1ALDH1A1L3MBTL1PARP1MPL | |
| SCHEMBL8977761 | 0.78 | F2RL3 (0.47) | ALDH1A1MPLSMN1; SMN2MEN1NPC1 | |
| SCHEMBL2748265 | 0.77 | ALDH1A1 (0.39) | AKR1B1ALDH1A1L3MBTL1PARP1MPL | |
| SCHEMBL25367519 | 0.77 | ALDH1A1 (0.39) | AKR1B1ALDH1A1L3MBTL1PARP1MPL | |
| SCHEMBL1913695 | 0.77 | ALDH1A1 (0.61) | AKR1B1ALDH1A1L3MBTL1MPLSMN1; SMN2 | |
| SCHEMBL22891451 | 0.75 | ALDH1A1 (0.38) | AKR1B1ALDH1A1L3MBTL1PARP1MPL | |
| SCHEMBL25369141 | 0.73 | PARP1 (0.39) | AKR1B1ALDH1A1L3MBTL1PARP1MPL | |
| SCHEMBL5591850 | 0.73 | APP (0.44) | AKR1B1ALDH1A1L3MBTL1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625973-B1 | METHOD FOR PREPARING 2-AMINO-4-NITROBENZOTHIAZOLE DERIVATIVES AND INTERMEDIATES | RHONE POULENC RORER SA (FR) | 1996-05-01 | — | — | EP | disclosed |
| EP-0625973-A1 | METHOD FOR PREPARING 2-AMINO 4-NITRO BENZOTHIAZOLE DERIVATIVES, AND INTERMEDIATES. | RHONE POULENC RORER SA (FR) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993012100-A1 | METHOD FOR PREPARING 2-AMINO 4-NITRO BENZOTHIAZOLE DERIVATIVES, AND INTERMEDIATES | RHONE-POULENC RORER S.A. (FR) | 1993-06-24 | — | — | WO | disclosed |