Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MPL | P40238 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818889 | 0.80 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1AKR1B1MPLMEN1 | |
| SCHEMBL22891113 | 0.80 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1AKR1B1MPLMEN1 | |
| SCHEMBL3067465 | 0.79 | PSMD14 (0.42) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL1913695 | 0.79 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1AKR1B1MPLMEN1 | |
| SCHEMBL2747730 | 0.79 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1AKR1B1MPLMEN1 | |
| SCHEMBL25367519 | 0.79 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1AKR1B1MPLMEN1 | |
| SCHEMBL8977752 | 0.77 | AKR1B1 (0.40) | ALDH1A1L3MBTL1AKR1B1MPLMEN1 | |
| SCHEMBL2252871 | 0.77 | PSMD14 (0.41) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL2256808 | 0.77 | PSMD14 (0.41) | ALDH1A1L3MBTL1MEN1KMT2ANPC1 | |
| Hydrogen Sulfide SCHEMBL27391083 | 0.77 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577240-B2 | Antiviral heteroaryl ketone derivatives | PFIZER INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20230339930-A1 | Antiviral Heteroaryl Ketone Derivatives | PFIZER INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339930-A1 | Antiviral Heteroaryl Ketone Derivatives | PFIZER INC. (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339930-A1 | Antiviral Heteroaryl Ketone Derivatives | PFIZER INC. (US) | 2023-10-26 | — | — | US | disclosed |
| EP-4178955-A1 | ANTIVIRAL HETEROARYL KETONE DERIVATIVES | Pfizer Inc. (US) | 2023-05-17 | — | — | EP | disclosed |
| WO-2022013684-A1 | ANTIVIRAL HETEROARYL KETONE DERIVATIVES | PFIZER INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| WO-2022013684-A1 | ANTIVIRAL HETEROARYL KETONE DERIVATIVES | PFIZER INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| CN-104478828-A | 2-amino-7-substituted benzothiazole compound as well as preparation method and application thereof | ZHANGZHOU PIEN TZE HUANG PHARM | 2015-04-01 | — | — | CN | disclosed |
| US-8178668-B2 | 2-aminopyridine kinase inhibitors | OSI Pharmaceuticals, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| EP-2265270-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009099982-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20090197862-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577240-B2 | Antiviral heteroaryl ketone derivatives | ACE2, SARS1, ACE | ALDH1A1 1752/4885L3MBTL1 1241/4885AKR1B1 785/4885 |
| US-20230339930-A1 | Antiviral Heteroaryl Ketone Derivatives | ACE2, ZC3HAV1, SARS1 | ALDH1A1 1519/4885L3MBTL1 489/4885AKR1B1 197/4885 |
| US-20090197862-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | ERBB2, ABL2, TIE1 | ALDH1A1 945/4885L3MBTL1 3088/4885AKR1B1 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.