SCHEMBL8977852

SCHEMBL8977852

Nc1cccc2nnnn12

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.34
LTK P29376 1/20 0.34
GRK5 P34947 1/20 0.34
CSNK1A1 P48729 1/20 0.34
LIMK1 P53667 1/20 0.34
TYRO3 Q06418 1/20 0.34
LRRK2 Q5S007 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
DYRK1B Q9Y463 1/20 0.34
ALDH1A1 P00352 2/20 0.32
BRD4 O60885 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
ADORA1 P30542 1/20 0.31
CREBBP Q92793 1/20 0.31
NUDT1 P36639 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22323396 0.74 CHEK1 (0.42) CHEK1LTKGRK5CSNK1A1LIMK1
SCHEMBL1187776 0.70
SCHEMBL18078709 0.69 EGLN2 (0.53) CHEK1LTKTYRO3LRRK2CLK4
SCHEMBL30359491 0.68 KDM4E (0.36) LTKCLK4
SCHEMBL9769233 0.67 KMT2A (0.33) ALDH1A1
SCHEMBL24656050 0.65 NUDT1 (0.59) CHEK1LTKLRRK2CLK4ALDH1A1
SCHEMBL18078708 0.65 ALDH1A1 (0.42) LTKCSNK1A1CLK4DYRK1BALDH1A1
SCHEMBL21083526 0.61 BRD4 (0.41) CHEK1LTKGRK5CSNK1A1LIMK1
SCHEMBL1602588 0.60 ADORA3 (0.54) ALDH1A1ADORA3L3MBTL1
SCHEMBL30001359 0.60 MAPT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709722-A1 Silver halide photographic element and method for stabilizing a light-sensitive silver halide emulsion MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-01 EP disclosed
US-4284713-A SILVER, SILVER HALIDE OR BINDER IMAGE, MASKING, EXPOSURE, DEVELOPMENT, DECOMPOSITION, ALKALI HALATE OR HALITE, ETCHING FUJI PHOTO FILM CO., LTD. (JP) 1981-08-18 US disclosed
US-4254214-A BLACK, REDUCTION OF COPPER SALT OR COMPLEX TO COPPER FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed