SCHEMBL8978050

SCHEMBL8978050

CNc1ccc(NC(=O)c2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.61
POLB P06746 3/20 0.61
NPC1 O15118 8/20 0.60
RAB9A P51151 8/20 0.60
MAPT P10636 6/20 0.59
RXFP1 Q9HBX9 2/20 0.59
LMNA P02545 2/20 0.59
APOBEC3G Q9HC16 1/20 0.59
KDM4E B2RXH2 1/20 0.59
MAPK1 P28482 1/20 0.59
CACNA1B Q00975 1/20 0.58
APBA1 Q02410 1/20 0.58
SMN1; SMN2 Q16637 6/20 0.57
PKM P14618 2/20 0.57
TP53 P04637 2/20 0.57
ALOX15 P16050 2/20 0.57
ATM Q13315 1/20 0.56
MEN1 O00255 2/20 0.55
APEX1 P27695 1/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8978184 1.00 KMT2A (0.61) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL18584099 0.95 PTPN1 (0.59) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL8420420 0.92 NPC1 (0.69) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL6459176 0.92 NPC1 (0.69) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL17013406 0.92 NPC1 (0.69) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL13380465 0.90 HDAC3 (0.54) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL14190785 0.90 PGR (0.59) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL13326007 0.90 KMT2A (0.52) KMT2APOLBNPC1RAB9AMAPT
SCHEMBL13380462 0.89 KMT2A (0.78) KMT2APOLBMAPTRXFP1LMNA
SCHEMBL912761 0.88 KMT2A (0.56) KMT2ANPC1RAB9AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026156-A1 BORATE SALTS, POLYMERS AND COMPOSITES UCHICAGO ARGONNE, LLC (US) 2024-01-25 US disclosed
US-11648759-B2 Electroconductive film, touch panel, and image display device DAI NIPPON PRINTING CO., LTD. (JP) 2023-05-16 US disclosed
US-11648759-B2 Electroconductive film, touch panel, and image display device DAI NIPPON PRINTING CO., LTD. (JP) 2023-05-16 US disclosed
US-11649358-B2 Borate salts, polymers and composites UCHICAGO ARGONNE, LLC (US) 2023-05-16 US disclosed
US-20180187958-A1 CERAMIC PLATE AND REFRIGERATOR INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-07-05 US disclosed
US-20180187958-A1 CERAMIC PLATE AND REFRIGERATOR INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-07-05 US disclosed
US-20170276840-A1 LAYERED BODY FOR OPTICAL MEMBER AND IMAGE DISPLAY DEVICE DAI NIPPON PRINTING CO.,LTD. (JP) 2017-09-28 US disclosed
US-9342008-B2 Fuser member compositions XEROX CORPORATION (US) 2016-05-17 US disclosed
US-9328199-B2 Cross-linked aramid UNIVERSIDAD DE BURGOS (ES) 2016-05-03 US disclosed
US-9315628-B2 Permanent attachment of agents to surfaces containing C-H functionality UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2016-04-19 US disclosed
US-20070191813-A1 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. 2007-08-16 US disclosed
US-20070191814-A1 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2007-08-16 US disclosed
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
US-7180172-B2 Circuits, multi-layer circuits, and methods of manufacture thereof WORLD PROPERTIES, INC. (US) 2007-02-20 US disclosed
US-20070021585-A1 Nucleophilic Acyl Substitution-based Polymerization Catalyzed by Oxometallic Complexes NATIONAL TAIWAN NORMAL UNIVERSITY (TW) 2007-01-25 US disclosed
US-20070015897-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070013102-A1 Method for making polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015899-A1 Polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015898-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240026156-A1 BORATE SALTS, POLYMERS AND COMPOSITES SLC26A3, SLC9A3, SLC9A1 KMT2A 1988/4885POLB 1253/4885NPC1 1555/4885
US-11649358-B2 Borate salts, polymers and composites SLC9A3, SLC26A3, SLC9A1 KMT2A 2083/4885POLB 1008/4885NPC1 1518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.