Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14334595 | 1.00 | LMNA (0.70) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL7764898 | 0.95 | LMNA (0.64) | LMNASMN1; SMN2 | |
| SCHEMBL9260881 | 0.94 | LMNA (0.62) | LMNA | |
| SCHEMBL8978138 | 0.94 | LMNA (0.62) | LMNA | |
| SCHEMBL20468079 | 0.93 | LMNA (0.60) | LMNASMN1; SMN2 | |
| SCHEMBL23633775 | 0.89 | LMNA (0.59) | LMNASMN1; SMN2 | |
| SCHEMBL21191482 | 0.88 | LMNA (0.54) | LMNA | |
| SCHEMBL6835459 | 0.88 | LMNA (0.53) | LMNA | |
| SCHEMBL6835457 | 0.88 | LMNA (0.53) | LMNA | |
| SCHEMBL12845762 | 0.88 | LMNA (0.53) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723709-B1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INT LTD (CH) | 2015-09-09 | — | — | EP | claimed |
| US-8835672-B2 | Manufacture of a triiodinated contrast agent | HOVIONE INTER LIMITED (CH) | 2014-09-16 | — | — | US | claimed |
| US-20140155648-A1 | Manufacture of a Triiodinated Contrast Agent | HOVIONE INTER LIMITED (CH) | 2014-06-05 | — | — | US | claimed |
| US-6262303-B1 | FROM THE COORRESPONDING DIACID CHLORIDE WITH 2-AMINO-1,3-PROPANEDIOL IN SOLVENT | DIBRA S.P.A. (IT) | 2001-07-17 | — | — | US | claimed |
| WO-2023117667-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOISOPHTHALIC BISAMIDES | BRACCO IMAGING SPA (IT) | 2023-06-29 | — | — | WO | disclosed |
| EP-3369724-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | Bracco Imaging SPA (IT) | 2018-09-05 | — | — | EP | disclosed |
| US-20170210692-A1 | METHOD FOR THE PREPARATION OF (S)-2-ACETYLOXYPROPIONIC ACID AND DERIVATIVES THEREOF | BRACCO IMAGING S.P.A. (IT) | 2017-07-27 | — | — | US | disclosed |
| EP-2365963-B1 | PROCESS FOR THE PREPARATION OF IODINATED CONTRAST AGENT | BRACCO IMAGING SPA (IT) | 2017-06-28 | — | — | EP | disclosed |
| US-20150329464-A1 | CONTINUOUS PROCESS FOR THE PREPARATION OF (S)-2-ACETYLOXYPROPIONIC ACID CHLORIDE | BRACCO IMAGING S.P.A. (IT) | 2015-11-19 | — | — | US | disclosed |
| EP-2723709-B1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INT LTD (CH) | 2015-09-09 | — | — | EP | disclosed |
| US-8835672-B2 | Manufacture of a triiodinated contrast agent | HOVIONE INTER LIMITED (CH) | 2014-09-16 | — | — | US | disclosed |
| US-8835672-B2 | Manufacture of a triiodinated contrast agent | HOVIONE INTER LIMITED (CH) | 2014-09-16 | — | — | US | disclosed |
| US-8624061-B2 | Process for the preparation of iodinated contrast agent | BRACCO IMAGING S.P.A. (IT) | 2014-01-07 | — | — | US | disclosed |
| US-8624061-B2 | Process for the preparation of iodinated contrast agent | BRACCO IMAGING S.P.A. (IT) | 2014-01-07 | — | — | US | disclosed |
| WO-2012175903-A1 | MANUFACTURE OF A TRIIODINATED CONTRAST AGENT | HOVIONE INTER. LTD (CH) | 2012-12-27 | — | — | WO | disclosed |
| US-20110207960-A1 | Process For The Preparation Of Iodinated Contrast Agent | BRACCO IMAGING S.P.A. (IT) | 2011-08-25 | — | — | US | disclosed |
| US-7368101-B2 | Process for the preparation of iopamidol and the new intermediates therein | BRACCO IMAGING S.P.A. (IT) | 2008-05-06 | — | — | US | disclosed |
| US-7368101-B2 | Process for the preparation of iopamidol and the new intermediates therein | BRACCO IMAGING S.P.A. (IT) | 2008-05-06 | — | — | US | disclosed |
| EP-1112247-B1 | A PROCESS FOR THE PREPARATION OF S-N,N'-BIS 2-HYDROXY-1- (HYDROXYMETHYL) ETHYL]-5- (2-HYDROXY-1- OXOPROPYL) AMINO]-2,4,6- TRIIODO-1,3- BENZENEDICARBOXAMIDE | BRACCO IMAGING SPA (IT) | 2003-04-16 | — | — | EP | disclosed |
| US-6350908-B1 | MULTISTAGE REACTION WITH AMIDATION OF ACYL HALIDES WITH AMINOALKANEDIOLS AND HYDROLYSIS | BRACCO IMAGING S.P.A (IT) | 2002-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329464-A1 | CONTINUOUS PROCESS FOR THE PREPARATION OF (S)-2-ACETYLOXYPROPIONIC ACID CHLORIDE | CLCN2, LPAR2, LPXN | LMNA 1549/4885SMN1; SMN2 2284/4885CYP2C19 1463/4885 |
| US-20110207960-A1 | Process For The Preparation Of Iodinated Contrast Agent | ITPR3, PPIP5K2, ITPR2 | LMNA 1081/4885SMN1; SMN2 4307/4885CYP2C19 3306/4885 |
| US-20170210692-A1 | METHOD FOR THE PREPARATION OF (S)-2-ACETYLOXYPROPIONIC ACID AND DERIVATIVES THEREOF | LDHA, ACACA, ADSL | LMNA 467/4885SMN1; SMN2 2894/4885CYP2C19 1937/4885 |
| US-20140155648-A1 | Manufacture of a Triiodinated Contrast Agent | SAT1, LYPLA2, AGPAT5 | LMNA 2871/4885SMN1; SMN2 4778/4885CYP2C19 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.