Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA4 | P22459 | 1/20 | 0.32 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.32 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24721803 | 0.79 | KCNA4 (0.32) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL3061881 | 0.77 | EPHX1 (0.39) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL14778808 | 0.75 | — | — | |
| SCHEMBL11824382 | 0.73 | — | — | |
| SCHEMBL20434892 | 0.72 | POLB (0.38) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL11912902 | 0.72 | EPHX1 (0.38) | KCNA4KCNA1KCNAB1 | |
| Hydrochloric Acid SCHEMBL25250172 | 0.72 | — | — | |
| SCHEMBL555211 | 0.71 | KCNA4 (0.37) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL19425925 | 0.71 | KCNA4 (0.37) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL10647773 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9044512-B2 | Amino alcohol cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140323548-A1 | NOVEL AMINO ALCOHOL CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2014-10-30 | — | — | US | disclosed |
| US-8802863-B2 | Amino alcohol cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130150625-A1 | Novel Amino Alcohol Cationic Lipids for Oligonucleotide Delivery | BANK OF AMERICA, N.A. | 2013-06-13 | — | — | US | disclosed |
| EP-2042532-B1 | Polymerizable composition and planographic printing plate precursor using the same, alkalisoluble polyurethane resin, and process for producing diol compound | FUJIFILM CORP (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-7741011-B2 | Polymerizable composition and planographic printing plate precursor using the same, alkali-soluble polyurethane resin, and process for producing diol compound | FUJIFILM CORPORATION (JP) | 2010-06-22 | — | — | US | disclosed |
| US-7741011-B2 | Polymerizable composition and planographic printing plate precursor using the same, alkali-soluble polyurethane resin, and process for producing diol compound | FUJIFILM CORPORATION (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20090087785-A1 | POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20090087785-A1 | POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| EP-2042532-A2 | Polymerizable composition and planographic printing plate precursor using the same, alkalisoluble polyrethane resin, an process for producing diol compound | FUJIFILM Corporation (JP) | 2009-04-01 | — | — | EP | disclosed |
| US-5482965-A | PROMOTERS FOR TRANSDERMAL ADMINISTRATION OF DRUGS | RAJADHYAKSHA VITHAL J (US) | 1996-01-09 | — | — | US | disclosed |
| EP-0576605-A4 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | RAJADHYAKSHA VITHAL J (US) | 1994-06-08 | — | — | EP | disclosed |
| EP-0576605-A1 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | THERAPEUTIC PATCH RESEARCH N.V. (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016236-A1 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | RAJADHYAKSHA VITHAL J (US) | 1992-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150625-A1 | Novel Amino Alcohol Cationic Lipids for Oligonucleotide Delivery | CETP, SLC7A5, NPC1L1 | KCNA4 3276/4885KCNA1 3938/4885KCNAB1 2333/4885 |
| US-20140323548-A1 | NOVEL AMINO ALCOHOL CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | CETP, SLC7A5, NPC1L1 | KCNA4 3276/4885KCNA1 3938/4885KCNAB1 2333/4885 |
| US-20090087785-A1 | POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND | PAH, RPN1, RER1 | KCNA4 4154/4885KCNA1 3728/4885KCNAB1 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.