SCHEMBL555211

SCHEMBL555211

CC1(N)COC(C)(C)OC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNA4 P22459 1/20 0.37
KCNA1 Q09470 1/20 0.37
KCNAB1 Q14722 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19425925 0.80 KCNA4 (0.37) KCNA4KCNA1KCNAB1
SCHEMBL83093 0.74
SCHEMBL3545805 0.72 KCNA4 (0.40) KCNA4KCNA1KCNAB1
SCHEMBL14649692 0.72 KCNA4 (0.40) KCNA4KCNA1KCNAB1
SCHEMBL3265548 0.72 KCNA4 (0.40) KCNA4KCNA1KCNAB1
SCHEMBL1471940 0.72 KCNA4 (0.40) KCNA4KCNA1KCNAB1
Hydrochloric Acid SCHEMBL15575093 0.72
SCHEMBL24721803 0.71 KCNA4 (0.32) KCNA4KCNA1KCNAB1
SCHEMBL8978150 0.71 KCNA4 (0.32) KCNA4KCNA1KCNAB1
SCHEMBL11819433 0.71 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194434-A1 POLYURETHANE, METHOD FOR PRODUCING POLYURETHANE, ELECTROCONDUCTIVE PASTE COMPOSITION, ELECTROCONDUCTIVE WIRE, AND METHOD FOR PRODUCING ELECTROCONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-14 EP disclosed
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed
CN-109983037-B Photoinitiator 科洛普拉斯特公司 2021-10-19 CN disclosed
EP-3545009-B1 PHOTOINITATORS COLOPLAST AS (DK) 2021-07-21 EP disclosed
EP-3545009-B1 PHOTOINITATORS COLOPLAST AS (DK) 2021-07-21 EP disclosed
US-10766906-B2 Fused hexacyclic imidazole derivatives as modulators of TNF activity UCB Biopharma SRL (BE) 2020-09-08 US disclosed
US-10696626-B2 Photoinitators COLOPLAST A/S (DK) 2020-06-30 US disclosed
US-10696626-B2 Photoinitators COLOPLAST A/S (DK) 2020-06-30 US disclosed
US-10669286-B2 Fused pentacyclic imidazole derivatives as modulators of TNF activity UCB Biopharma SRL (BE) 2020-06-02 US disclosed
US-20100217000-A1 Process for the Preparation of Thiazolopyrimidines ASTRAZENECA AB (SE) 2010-08-26 US disclosed
WO-2010096320-A2 CONTROLLED RELEASE OF NITRIC OXIDE AND DRUGS FROM FUNCTIONALIZED MACROMERS AND OLIGOMERS BEZWADA BIOMEDICAL, LLC (US) 2010-08-26 WO disclosed
US-20100209469-A1 Controlled Release of Nitric Oxide And Drugs From Functionalized Macromers And Oligomers BEZWADA BIOMEDICAL, LLC. (US) 2010-08-19 US disclosed
US-20100209469-A1 Controlled Release of Nitric Oxide And Drugs From Functionalized Macromers And Oligomers BEZWADA BIOMEDICAL, LLC. (US) 2010-08-19 US disclosed
US-20100209469-A1 Controlled Release of Nitric Oxide And Drugs From Functionalized Macromers And Oligomers BEZWADA BIOMEDICAL, LLC. (US) 2010-08-19 US disclosed
EP-1711505-B1 PROCESS FOR THE PREPARATION OF THIAZOLOPYRIMIDINES ASTRAZENECA AB (SE) 2010-06-23 EP disclosed
US-20090043097-A1 Methods ASTRAZENECA AB (SE) 2009-02-12 US disclosed
US-20070282103-A1 Process for the Preparation of Thiazolopyrimidines ASTRAZENECA AB (SE) 2007-12-06 US disclosed
EP-1711505-A2 PROCESS FOR THE PREPARATION OF THIAZOLOPYRIMIDINES AstraZeneca AB (SE) 2006-10-18 EP disclosed
WO-2005056563-A2 PROCESS FOR THE PREPARATION OF THIAZOLOPYRIMIDINES ASTRAZENECA AB (SE) 2005-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043097-A1 Methods CYP21A2, CYP17A1, HSD17B7 KCNA4 1632/4885KCNA1 2056/4885KCNAB1 1686/4885
US-20070282103-A1 Process for the Preparation of Thiazolopyrimidines TPMT, TYMP, DPYD KCNA4 1625/4885KCNA1 3319/4885KCNAB1 3371/4885
US-20100209469-A1 Controlled Release of Nitric Oxide And Drugs From Functionalized Macromers And Oligomers NOS2, NOS1, NOS3 KCNA4 3568/4885KCNA1 3208/4885KCNAB1 4510/4885
US-10766906-B2 Fused hexacyclic imidazole derivatives as modulators of TNF activity TNF, TNFRSF1A, NFKBIA KCNA4 640/4885KCNA1 384/4885KCNAB1 346/4885
US-10669286-B2 Fused pentacyclic imidazole derivatives as modulators of TNF activity TNF, TNFRSF1A, NFKBIA KCNA4 1785/4885KCNA1 1528/4885KCNAB1 724/4885
US-20100217000-A1 Process for the Preparation of Thiazolopyrimidines TPMT, TYMP, DPYD KCNA4 1248/4885KCNA1 2806/4885KCNAB1 2804/4885
US-10696626-B2 Photoinitators CRY1, QDPR, CRY2 KCNA4 4527/4885KCNA1 4335/4885KCNAB1 4058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.