Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978466 | 0.81 | AGTR2 (0.44) | MEN1ALDH1A1MAPK1KMT2AUGCG | |
| SCHEMBL8542880 | 0.74 | AOC3 (0.41) | POLBMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL8548253 | 0.67 | MTNR1A (0.51) | MTNR1AMTNR1BCA1CA2ACHE | |
| SCHEMBL8545606 | 0.67 | AOC3 (0.45) | POLBUGCGMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL9186638 | 0.66 | MTNR1A (0.50) | POLBALDH1A1MTNR1AMTNR1BRAB9A | |
| SCHEMBL7100679 | 0.63 | POLB (0.55) | POLBMEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL14380839 | 0.62 | ACACB (0.67) | POLBMEN1MAPK1KMT2AMTNR1A | |
| SCHEMBL6969020 | 0.62 | ACACB (0.67) | POLBMEN1MAPK1KMT2AMTNR1A | |
| SCHEMBL11604883 | 0.61 | AOC3 (0.62) | ALDH1A1MAPK1MTNR1AMTNR1BRAB9A | |
| SCHEMBL29676292 | 0.60 | MTNR1A (0.56) | ALDH1A1MTNR1AMTNR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510376-A | TREATING DIABETES, HYPERGLYCEMIA, OBESITY | AMERICAN CYANAMID COMPANY (US) | 1996-04-23 | — | — | US | disclosed |