Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 8/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978468 | 0.81 | POLB (0.40) | MTNR1AMTNR1BMEN1ALDH1A1MAPK1 | |
| SCHEMBL8593552 | 0.80 | ADRB3 (0.45) | AGTR2 | |
| SCHEMBL8545450 | 0.79 | AGTR2 (0.40) | AGTR2ACACBAGTR1MTNR1AMTNR1B | |
| SCHEMBL9410787 | 0.78 | AGTR2 (0.44) | AGTR2AGTR1KMT2ALRRK2 | |
| SCHEMBL8548581 | 0.75 | CA1 (0.47) | AGTR2ACACBAGTR1MTNR1AMTNR1B | |
| SCHEMBL8540992 | 0.74 | AGTR2 (0.44) | AGTR2AGTR1CA1CA2ACHE | |
| SCHEMBL8549721 | 0.72 | AGTR2 (0.44) | AGTR2AGTR1MTNR1AMTNR1B | |
| SCHEMBL9410814 | 0.70 | MAOB (0.36) | AGTR2AGTR1LRRK2 | |
| SCHEMBL8547546 | 0.68 | CA1 (0.46) | AGTR2AGTR1MTNR1AMTNR1BMEN1 | |
| SCHEMBL8549143 | 0.66 | ADRA1A (0.42) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510376-A | TREATING DIABETES, HYPERGLYCEMIA, OBESITY | AMERICAN CYANAMID COMPANY (US) | 1996-04-23 | — | — | US | disclosed |