SCHEMBL8978705

SCHEMBL8978705

Cc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1S(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.47
ALDH1A1 P00352 6/20 0.47
LMNA P02545 4/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
POLB P06746 2/20 0.46
MAPT P10636 1/20 0.46
HTR2C P28335 2/20 0.45
HTR2B P41595 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
SFRP1 Q8N474 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NAMPT P43490 1/20 0.44
GAA P10253 2/20 0.43
HPGD P15428 1/20 0.43
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4616004 0.88 LMNA (0.45) HSD11B1ALDH1A1LMNATSHRHTT
SCHEMBL15867387 0.88 HSD11B1 (0.47) HSD11B1ALDH1A1LMNATSHRHTT
SCHEMBL11599302 0.83 ALDH1A1 (0.66) ALDH1A1LMNATSHRHTTNPSR1
SCHEMBL20408989 0.83 ALDH1A1 (0.47) HSD11B1ALDH1A1TSHRSMN1; SMN2POLB
SCHEMBL9756854 0.81 ALDH1A1 (0.47) ALDH1A1LMNATSHRHTTNPSR1
SCHEMBL23105038 0.81 KMT2A (0.48) HSD11B1ALDH1A1LMNANPSR1MAPT
SCHEMBL8474567 0.80 KMT2A (0.50) ALDH1A1TSHRSMN1; SMN2POLBMAPT
SCHEMBL17245005 0.79 TSHR (0.49) HSD11B1ALDH1A1TSHRSMN1; SMN2POLB
SCHEMBL1585056 0.79 HSD11B1 (0.59) HSD11B1ALDH1A1LMNATSHRHTT
SCHEMBL31356933 0.79 NAMPT (0.47) HSD11B1TSHRMAPTHTR2CFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US claimed
EP-0411625-B1 Method to produce poly(arylene sulfide/sulfone) polymer PHILLIPS PETROLEUM CO (US) 1996-05-08 EP disclosed
US-5350834-A Thermal stability and purity, zinc compound PHILLIPS PETROLEUM COMPANY (US) 1994-09-27 US disclosed
US-5331069-A Method of treating poly(arylene sulfide sulfone) polymers and polymers PHILLIPS PETROLEUM COMPANY (US) 1994-07-19 US disclosed
US-5298574-A Copolymerizing in presence of n-methyl-2-pyrrolidone, sodium carbonate and sodium hydrogen sulfide PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
US-5298573-A Poly(arylene sulfide sulfone)/poly(arylene sulfide ketone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-03-29 US disclosed
US-5286817-A Poly(arylene sulfide)/poly(arylene sulfide sulfone) block copolymers and preparation thereof PHILLIPS PETROLEUM COMPANY (US) 1994-02-15 US disclosed
US-5235034-A Increased melt stability and decreased impurities PHILLIPS PETROLEUM COMPANY (US) 1993-08-10 US disclosed
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US disclosed
US-5177174-A Branched aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1993-01-05 US disclosed
EP-0280325-A2 Melt stabilization of poly (arylene sulfide sulfone) S PHILLIPS PETROLEUM COMPANY (US) 1988-08-31 EP disclosed
EP-0033906-B1 PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1985-05-15 EP disclosed
US-4301274-A BY REACTING A DIHALOAROMATIC SULFONE, AND AN ALKALI METAL SULFIDE; ENDCAPPING PHILLIPS PETROLEUM COMPANY (US) 1981-11-17 US disclosed
EP-0033906-A1 Process for the production of aromatic sulfide/sulfone polymers PHILLIPS PETROLEUM COMPANY (US) 1981-08-19 EP disclosed
US-4127713-A FORM A DIHALOAROMATIC SULFONE, ALKALI METAL SULFIDE, AMIDE, SODIUM CARBOXYLATE AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-11-28 US disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed
US-4102875-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-07-25 US disclosed
US-4070349-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-01-24 US disclosed
US-4016145-A SULFONE POLYMERSREACTING A DIHALO AROMATIC SULFONE, AN ALKALI METAL SULFIDE, AN ALKALI METAL CARBOXYLATE, AND AN AMIDE PHILLIPS PETROLEUM COMPANY (US) 1977-04-05 US disclosed