Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403008 | 0.89 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL4618045 | 0.87 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL4617585 | 0.87 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL30963734 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL757794 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL4402282 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL4638498 | 0.84 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL12336792 | 0.84 | HTR6 (0.58) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 | |
| SCHEMBL4400959 | 0.84 | HTR6 (0.56) | ALDH1A1SMN1; SMN2POLBMAPTL3MBTL1 | |
| SCHEMBL8978705 | 0.83 | HSD11B1 (0.47) | ALDH1A1SMN1; SMN2POLBMAPTSFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069205-A | FROM BI- OR TRI-PHENYLENE SULFIDE, AROMATIC ETHER, AND ISOPHTHALOYL OR TEREPHTHALOYL HALIDE | UNIVERSITY PATENTS, INC. (US) | 1978-01-17 | — | — | US | disclosed |