Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513221 | 0.84 | MMP8 (0.50) | MMP8NLRP3PIN1MEN1NPC1 | |
| SCHEMBL1294071 | 0.84 | MMP8 (0.44) | MMP8NLRP3CA12CA1CA2 | |
| SCHEMBL2964984 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2TSHRTDP1ALDH1A1 | |
| SCHEMBL30534792 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2TSHRL3MBTL1TDP1 | |
| SCHEMBL2761315 | 0.78 | CYP4F2 (0.53) | MMP8NLRP3PIN1MEN1NPC1 | |
| SCHEMBL10798591 | 0.77 | MMP8 (0.46) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL7509738 | 0.75 | MMP8 (0.51) | MMP8NLRP3PIN1MEN1NPC1 | |
| SCHEMBL7619852 | 0.74 | MMP8 (0.44) | MMP8NLRP3PIN1MEN1NPC1 | |
| Pyrrolidine SCHEMBL4728724 | 0.74 | SLC6A2 (0.36) | NLRP3MEN1NPC1KMT2A | |
| SCHEMBL1044283 | 0.74 | NLRP3 (0.50) | MMP8NLRP3PIN1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455313-B1 | Process for polymerization of olefins and polymerization catalyst | MITSUI PETROCHEMICAL IND (JP) | 1996-05-08 | — | — | EP | disclosed |