SCHEMBL10798591

SCHEMBL10798591

CCCc1ccccc1C(C(=O)OCC)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.46
CYP4F2 P78329 2/20 0.44
CYP4A11 Q02928 2/20 0.44
PIN1 Q13526 1/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
KMT2A Q03164 1/20 0.41
POLB P06746 1/20 0.41
CYSLTR2 Q9NS75 6/20 0.40
CYSLTR1 Q9Y271 6/20 0.40
ALDH1A1 P00352 1/20 0.40
CASP1 P29466 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7513221 0.88 MMP8 (0.50) MMP8CYP4F2CYP4A11PIN1TSHR
SCHEMBL7619852 0.87 MMP8 (0.44) MMP8CYP4F2CYP4A11PIN1TSHR
SCHEMBL4027761 0.85 CASP1 (0.44) MMP8CYP4F2CYP4A11PIN1TSHR
SCHEMBL2761315 0.85 CYP4F2 (0.53) MMP8CYP4F2CYP4A11PIN1TSHR
SCHEMBL27622171 0.81 MMP8 (0.46) MMP8CYP4F2CYP4A11PIN1TSHR
SCHEMBL10958632 0.80 L3MBTL1 (0.44) MMP8CYP4F2CYP4A11PIN1TSHR
SCHEMBL7509738 0.79 MMP8 (0.51) MMP8PIN1TSHRMEN1NPC1
SCHEMBL27603380 0.78 CYP4F2 (0.49) MMP8CYP4F2CYP4A11PIN1TSHR
SCHEMBL1044283 0.77 NLRP3 (0.50) MMP8PIN1TSHRMEN1NPC1
SCHEMBL8979046 0.77 MMP8 (0.43) MMP8CYP4F2CYP4A11PIN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4676924-A Liquid crystalline isothiocyanates with dioxane ring and liquid crystalline admixtures containing same WOJSKOWA AKADEMIA TECHNICZNA (PL) 1987-06-30 US disclosed
EP-0170082-A2 Liquid crystalline isothiocyanates with a dioxane ring and liquid crystalline admixtures containing the same Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) 1986-02-05 EP disclosed