SCHEMBL8979164

SCHEMBL8979164

COC(=O)C(CCCN)(CCCN)C(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 2/20 0.36
FDPS P14324 1/20 0.35
PDE3A Q14432 1/20 0.35
PAOX Q6QHF9 4/20 0.34
CYP1A2 P05177 2/20 0.34
LMNA P02545 2/20 0.34
BLM P54132 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTPRB P23467 4/20 0.33
DGAT1 O75907 1/20 0.32
TSHR P16473 2/20 0.32
GABRR3 A8MPY1 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
HDAC3 O15379 1/20 0.32
GABBR2 O75899 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8641534 0.98 LMNA (0.37) ODC1FDPSPDE3APAOXCYP1A2
SCHEMBL8633741 0.80 FDPS (0.39) ODC1FDPSPDE3APAOXCYP1A2
SCHEMBL13689469 0.80 CYP4F2 (0.40) ODC1FDPSPDE3APAOXCYP1A2
SCHEMBL15233853 0.79 EPHX1 (0.39) FDPSLMNAMAPTPTPRBDGAT1
SCHEMBL27593964 0.78 ODC1 (0.38) ODC1FDPSPDE3APAOXCYP1A2
SCHEMBL8979106 0.78 MEN1 (0.53) CYP1A2LMNAKDM4EMAPTSMN1; SMN2
SCHEMBL6595080 0.78 ODC1 (0.38) ODC1FDPSPDE3APAOXCYP1A2
SCHEMBL28012765 0.78 ODC1 (0.37) ODC1FDPSPDE3APAOXCYP1A2
SCHEMBL7203818 0.78 ODC1 (0.38) ODC1FDPSPDE3APAOXCYP1A2
SCHEMBL7203815 0.78 ODC1 (0.38) ODC1FDPSPDE3APAOXCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5552507-A DI-(3-ISOCYANATOPROPYL) MALONIC ACID DIESTERS, MONOMERS FOR POLYURETHANES OR POLYUREAS THAT ARE PHOTOSTABLE AND WEATHER RESISTANT BAYER AKTIENGESELLSCHAFT (DE) 1996-09-03 US disclosed