SCHEMBL8633741

SCHEMBL8633741

COC(=O)C(O)(CCCN)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.39
PDE3A Q14432 2/20 0.39
ODC1 P11926 2/20 0.35
PAOX Q6QHF9 4/20 0.33
LMNA P02545 3/20 0.33
BLM P54132 2/20 0.33
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ADRB3 P13945 1/20 0.32
PDE4D Q08499 1/20 0.32
DGAT1 O75907 1/20 0.31
TSHR P16473 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
HDAC3 O15379 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633101 0.92 FDPS (0.42) FDPSPDE3APAOXLMNABLM
SCHEMBL8629503 0.89 LMNA (0.36) FDPSPDE3ALMNAKDM4EMAPT
SCHEMBL27593964 0.81 ODC1 (0.38) FDPSPDE3AODC1PAOXLMNA
SCHEMBL8979164 0.80 ODC1 (0.36) FDPSPDE3AODC1PAOXLMNA
Hydrochloric Acid SCHEMBL8641534 0.78 LMNA (0.37) FDPSPDE3AODC1PAOXLMNA
SCHEMBL13689469 0.78 CYP4F2 (0.40) FDPSPDE3AODC1PAOXLMNA
SCHEMBL27594000 0.78 FDPS (0.35) FDPSPDE3AODC1PAOXLMNA
SCHEMBL28012765 0.77 ODC1 (0.37) FDPSPDE3AODC1PAOXLMNA
SCHEMBL7203818 0.77 ODC1 (0.38) FDPSPDE3AODC1PAOXLMNA
SCHEMBL6595080 0.77 ODC1 (0.38) FDPSPDE3AODC1PAOXLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773465-A Tartronic acids, their acetalic ethers and o-esters DOMPE FARMACEUTICI S.P.A. (IT) 1998-06-30 US disclosed
US-5656656-A Tartronic acids, their acetalic ethers and O-esters DOMPE FARMACEUTICI S.P.A. (IT) 1997-08-12 US disclosed
EP-0667850-B1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE FARMACEUTICI SPA (IT) 1997-05-28 EP disclosed
EP-0667850-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. DOMPE FARMACEUTICI SPA (IT) 1995-08-23 EP disclosed
CN-1091741-A Tartronic acid and acetal ether thereof and O-ester DOMPE FARMACEUTICI SPA (IT) 1994-09-07 CN disclosed
WO-1994010127-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE' FARMACEUTICI S.P.A. (IT) 1994-05-11 WO disclosed