Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446818 | 0.88 | APEX1 (0.57) | NPC1KMT2AAPEX1LMNAMAPT | |
| SCHEMBL9696207 | 0.77 | SGMS2 (0.66) | NPC1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL5839896 | 0.74 | ALDH1A1 (0.54) | NPC1KMT2AAPEX1LMNAMAPT | |
| SCHEMBL489857 | 0.74 | ALDH1A1 (0.48) | KMT2ALMNAMAPTALDH1A1PARP1 | |
| SCHEMBL5839695 | 0.73 | APEX1 (0.56) | NPC1KMT2AAPEX1LMNAMAPT | |
| SCHEMBL12301135 | 0.73 | KDM4E (0.47) | NPC1RAB9AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL2089466 | 0.72 | KMT2A (0.57) | NPC1KMT2AAPEX1LMNAMAPT | |
| SCHEMBL206583 | 0.72 | HCRTR1 (0.66) | KMT2ARAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL10451670 | 0.71 | KDM4E (0.49) | KMT2ALMNAMAPTALDH1A1HTT | |
| SCHEMBL5839915 | 0.71 | APEX1 (0.53) | NPC1KMT2ARAB9AAPEX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512486-A | Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions | NORTHEASTERN UNIVERSITY (US) | 1996-04-30 | — | — | US | disclosed |