Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715644 | 0.90 | ELANE (0.53) | KDM4EALDH1A1ELANENPSR1KMT2A | |
| SCHEMBL1434118 | 0.87 | ALDH1A1 (0.59) | KDM4EALDH1A1PRMT5MRGPRX1NPSR1 | |
| SCHEMBL11784830 | 0.86 | ALDH1A1 (0.57) | KDM4EALDH1A1PRMT5MRGPRX1NPSR1 | |
| SCHEMBL17859344 | 0.86 | LMNA (0.60) | KDM4EALDH1A1PRMT5CYP1A2CYP2C9 | |
| SCHEMBL6789664 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1PRMT5POLBMRGPRX1 | |
| SCHEMBL3441526 | 0.86 | HTT (0.54) | KDM4EALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL11784824 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1PRMT5POLBMRGPRX1 | |
| SCHEMBL27994489 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1PRMT5POLBMRGPRX1 | |
| SCHEMBL10499645 | 0.83 | SLC6A3 (0.54) | KDM4EALDH1A1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL11786107 | 0.83 | MEN1 (0.59) | KDM4EALDH1A1PRMT5POLBMRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2204471-A | — | — | None | — | — | JP | disclosed |
| CN-1013671-B | PREPARATION METHOD FOR PYRAZOLINES | SCHERING AG (DE) | 1991-08-28 | — | — | CN | disclosed |
| JP-H02204471-A | PRODUCTION OF ARYLMETHYL (TRIFLUOROETHOXYPHENYL)KETONE | RHONE POULENC CHIM | 1990-08-14 | — | — | JP | disclosed |
| CN-86108628-A | Preparation method for pyrazolines | — | 1987-07-01 | — | — | CN | disclosed |