Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979256 | 0.88 | NPC1 (0.47) | APEX1ALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL5839896 | 0.86 | ALDH1A1 (0.54) | APEX1ALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL5839695 | 0.85 | APEX1 (0.56) | APEX1ALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL5839915 | 0.83 | APEX1 (0.53) | APEX1ALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL28501298 | 0.81 | APEX1 (0.67) | APEX1ALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL2452574 | 0.80 | LMNA (0.68) | ALDH1A1KMT2APTK2BKDM4ENPC1 | |
| SCHEMBL28758280 | 0.80 | NPC1 (0.56) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL5839124 | 0.79 | SGMS2 (0.60) | APEX1ALDH1A1KMT2APTK2BHTT | |
| SCHEMBL112903 | 0.79 | SGMS2 (0.66) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL29433417 | 0.79 | SGMS2 (0.66) | ALDH1A1KMT2APTK2BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591276-A | Dendritic self-assembly optical nonlinear chromophore and synthetic method and application thereof | 广州大学 | 2022-06-07 | — | — | CN | claimed |
| CN-114656432-B | Self-assembled organic optical nonlinear chromophore, and synthesis method and application thereof | 广州大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-114656432-A | Self-assembled organic optical nonlinear chromophore and synthetic method and application thereof | 广州大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114591276-A | Dendritic self-assembly optical nonlinear chromophore and synthetic method and application thereof | 广州大学 | 2022-06-07 | — | — | CN | disclosed |
| US-8022072-B2 | Azolylmethylidenehydrazine derivative and use thereof | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| EP-2168951-A1 | AZOLYLMETHYLENEHYDRAZINE DERIVATIVE AND USE THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2010-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190754-A1 | AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF | ARSA, AHR, HRH2 | APEX1 3835/4885ALDH1A1 831/4885KMT2A 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.