Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | TK1 | P04183 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505629 | 0.87 | TDP1 (0.36) | KIF11TK1CYP2C9CYP2C19ALOX15 | |
| SCHEMBL21351764 | 0.80 | KIF11 (0.37) | KIF11TK1CYP2C9CYP2C19ALOX15 | |
| SCHEMBL27739758 | 0.74 | KIF11 (0.41) | KIF11CYP2C9CYP2C19ALOX15TSHR | |
| SCHEMBL465453 | 0.74 | CYP2C19 (0.39) | KIF11CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL8587208 | 0.72 | TK1 (0.44) | KIF11TK1CYP2C9CYP2C19ALOX15 | |
| SCHEMBL10438660 | 0.72 | TK1 (0.44) | KIF11TK1CYP2C9CYP2C19ALOX15 | |
| SCHEMBL8979349 | 0.71 | CYP2C19 (0.35) | KIF11CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL16551069 | 0.71 | LMNA (0.42) | KIF11CYP2C19ALOX15TSHRALDH1A1 | |
| SCHEMBL3529956 | 0.71 | TRPA1 (0.38) | KIF11CYP2C19ALOX15ALDH1A1CYP1A2 | |
| SCHEMBL3529955 | 0.71 | TRPA1 (0.38) | KIF11CYP2C19ALOX15ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775149-B1 | NOVEL PROTECTING GROUPS AND USE THEREOF IN AN IMPROVED PROCESS FOR OLIGONUCLEOTIDE SYNTHESIS | UNIV COLORADO (US) | 2004-09-22 | — | — | EP | disclosed |
| US-6008400-A | MIXING TRIMETHYLORTHOFORMATE AND AN ALCOHOL IN A SOLVENT TO PRODUCE A REACTION MIXTURE AND REMOVING THE SOLVENT TO YIELD ORTHOESTER REAGENT | REGENTS OF THE UNIVERSITY OF COLORADO, THE | 1999-12-28 | — | — | US | disclosed |
| US-5889136-A | PHOSPHORAMIDITE OLIGONUCLEOTIDE BIOSYNTHESIS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1999-03-30 | — | — | US | disclosed |