Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979391 | 1.00 | KMT2A (0.40) | KMT2AMEN1RAB9ATXNRD1VCAM1 | |
| SCHEMBL8979366 | 1.00 | KMT2A (0.40) | KMT2AMEN1RAB9ATXNRD1VCAM1 | |
| SCHEMBL10434005 | 0.86 | VCAM1 (0.35) | KMT2AMEN1RAB9ATXNRD1VCAM1 | |
| SCHEMBL10433856 | 0.86 | VCAM1 (0.35) | KMT2AMEN1RAB9ATXNRD1VCAM1 | |
| SCHEMBL10433857 | 0.86 | VCAM1 (0.35) | KMT2AMEN1RAB9ATXNRD1VCAM1 | |
| SCHEMBL8979406 | 0.84 | PTGS2 (0.36) | KMT2ACA9LMNAPTGS2ALDH1A1 | |
| SCHEMBL8979377 | 0.84 | PTGS2 (0.36) | KMT2ACA9LMNAPTGS2ALDH1A1 | |
| SCHEMBL10434021 | 0.80 | ATM (0.35) | RAB9ATXNRD1VCAM1LMNARECQL | |
| SCHEMBL10434023 | 0.80 | ATM (0.35) | RAB9ATXNRD1VCAM1LMNARECQL | |
| SCHEMBL7518047 | 0.77 | TXNRD1 (0.33) | RAB9ATXNRD1VCAM1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | claimed |
| US-5136059-A | PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-04 | — | — | US | claimed |
| EP-0322815-A2 | Propoxybenzene derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | claimed |