Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | MAX | P61244 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031043 | 1.00 | TXNRD1 (0.33) | TXNRD1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL10434023 | 0.85 | ATM (0.35) | TXNRD1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL10434021 | 0.85 | ATM (0.35) | TXNRD1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL2923101 | 0.81 | LMNA (0.39) | ATMTDP1ALDH1A1HIF1ASRD5A2 | |
| SCHEMBL8979401 | 0.81 | LMNA (0.39) | ATMTDP1ALDH1A1HIF1ASRD5A2 | |
| SCHEMBL1496810 | 0.81 | LMNA (0.39) | ATMTDP1ALDH1A1HIF1ASRD5A2 | |
| SCHEMBL10433857 | 0.81 | VCAM1 (0.35) | TXNRD1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL10433856 | 0.81 | VCAM1 (0.35) | TXNRD1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL10434005 | 0.81 | VCAM1 (0.35) | TXNRD1ATMTDP1ALDH1A1HIF1A | |
| SCHEMBL7031666 | 0.80 | ATM (0.33) | TXNRD1ATMTDP1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1438981-A | Process for preparing R-1- (aryloxy) propan-2-ol | RHODIA CHIREX INC (US) | 2003-08-27 | — | — | CN | disclosed |
| US-6448449-B2 | RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; | RHODIA CHIREX, INC. | 2002-09-10 | — | — | US | disclosed |
| US-6448449-B2 | RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; | RHODIA CHIREX, INC. | 2002-09-10 | — | — | US | disclosed |
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | RHODIA CHIREX, INC. | 2002-01-17 | — | — | US | disclosed |
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | RHODIA CHIREX, INC. | 2002-01-17 | — | — | US | disclosed |
| WO-2001081286-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | RHODIA/CHIREX, INC. (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | TOP1, POLN, RIF1 | TXNRD1 1526/4885ATM 3082/4885TDP1 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.