Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044976 | 1.00 | ALDH1A1 (0.39) | ALDH1A1METAP2CYP2D6MEN1KMT2A | |
| SCHEMBL8374251 | 1.00 | ALDH1A1 (0.39) | ALDH1A1METAP2CYP2D6MEN1KMT2A | |
| SCHEMBL29198506 | 1.00 | ALDH1A1 (0.39) | ALDH1A1METAP2CYP2D6MEN1KMT2A | |
| SCHEMBL7263222 | 0.86 | RAB9A (0.35) | MEN1KMT2ASLC6A3RAB9ATSHR | |
| SCHEMBL13983475 | 0.86 | RAB9A (0.35) | MEN1KMT2ASLC6A3RAB9ATSHR | |
| SCHEMBL7263221 | 0.86 | RAB9A (0.35) | MEN1KMT2ASLC6A3RAB9ATSHR | |
| SCHEMBL8632433 | 0.86 | ALDH1A1 (0.40) | ALDH1A1METAP2CYP2D6MEN1KMT2A | |
| SCHEMBL10493718 | 0.85 | METAP2 (0.38) | ALDH1A1METAP2MEN1KMT2ACYP2C19 | |
| SCHEMBL14017319 | 0.85 | ALDH1A1 (0.37) | ALDH1A1METAP2CYP2D6MEN1KMT2A | |
| SCHEMBL2380756 | 0.84 | SLC6A3 (0.43) | ALDH1A1MEN1KMT2ASLC6A3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425661-A | Macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2024-01-19 | — | — | CN | disclosed |
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5312999-A | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5136059-A | PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0301587-B1 | LIQUID CRYSTAL COMPOUNDS AND INTERMEDIATES THEREOF | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5114615-A | Compounds for optical apparatus | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0357850-A1 | Polymer composition, capable of forming a chiral nematic mesophase | STAMICARBON B.V. (NL) | 1990-03-14 | — | — | EP | disclosed |
| EP-0322815-A2 | Propoxybenzene derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0301587-A1 | Liquid crystal compounds and intermediates thereof | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-01 | — | — | EP | disclosed |