Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567550 | 0.85 | KDM4E (0.46) | ALDH1A1MAPTKDM4ETSHRGAA | |
| SCHEMBL8979487 | 0.81 | FPR1 (0.48) | ALDH1A1MAPTKDM4ETSHRGAA | |
| SCHEMBL14254903 | 0.79 | TSHR (0.68) | ALDH1A1MAPTKDM4ETSHRGAA | |
| SCHEMBL8566126 | 0.78 | KMT2A (0.41) | ALDH1A1MAPTKDM4ETSHRGAA | |
| SCHEMBL6993599 | 0.77 | KMT2A (0.55) | ALDH1A1MAPTKDM4ETSHRLMNA | |
| SCHEMBL8979498 | 0.77 | MAPT (0.47) | ALDH1A1MAPTKDM4ETSHRGAA | |
| SCHEMBL8567545 | 0.73 | MAPT (0.42) | ALDH1A1MAPTKDM4ETSHRGAA | |
| SCHEMBL8564179 | 0.73 | KDM4E (0.48) | ALDH1A1MAPTKDM4ETSHRGAA | |
| SCHEMBL5226002 | 0.72 | TDP1 (0.54) | MAPTKDM4EGAATDP1LMNA | |
| SCHEMBL145084 | 0.71 | APLNR (0.68) | ALDH1A1MAPTTSHRGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710725-A1 | Production of optically active compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |