Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979522 | 0.85 | TRPV1 (0.36) | TRIM24TRPV1CYP11B1CYP11B2 | |
| SCHEMBL8979497 | 0.80 | ALOX5 (0.36) | TRPV1CYP11B1CYP11B2 | |
| SCHEMBL8979548 | 0.80 | TRIM24 (0.39) | TRIM24TRPV1CYP11B1CYP11B2 | |
| SCHEMBL8979490 | 0.78 | ATAD2 (0.42) | CYP11B1CYP11B2 | |
| SCHEMBL8979495 | 0.74 | TRIM24 (0.35) | TRIM24TRPV1CYP11B1CYP11B2 | |
| SCHEMBL8557669 | 0.74 | TRIM24 (0.35) | TRIM24TRPV1CYP11B1CYP11B2XIAP | |
| SCHEMBL8979482 | 0.72 | ALOX5 (0.34) | TRIM24CYP11B1CYP11B2 | |
| SCHEMBL8979542 | 0.70 | TRPV1 (0.36) | TRPV1CYP11B1CYP11B2 | |
| SCHEMBL8979508 | 0.70 | ALOX5 (0.46) | TRIM24TRPV1CYP11B1CYP11B2 | |
| SCHEMBL8979500 | 0.68 | ALOX5 (0.38) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |