Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979610 | 0.83 | ATAD2 (0.43) | ATAD2ALDH1A1GAALMNAMAPT | |
| SCHEMBL8979548 | 0.78 | TRIM24 (0.39) | ALDH1A1GAACYP11B1CYP11B2 | |
| SCHEMBL8979491 | 0.78 | TRIM24 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL8979522 | 0.74 | TRPV1 (0.36) | CYP11B1CYP11B2HTR6 | |
| SCHEMBL8979552 | 0.73 | ATAD2 (0.32) | ATAD2DRD3 | |
| SCHEMBL8556514 | 0.73 | ATAD2 (0.39) | ATAD2ALDH1A1GAALMNAMAPT | |
| SCHEMBL8979492 | 0.73 | ATAD2 (0.39) | ATAD2ALDH1A1GAALMNAMAPT | |
| SCHEMBL8556509 | 0.67 | ATAD2 (0.61) | ATAD2ALDH1A1GAALMNAMAPT | |
| SCHEMBL8979497 | 0.66 | ALOX5 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL9159708 | 0.64 | DRD2 (0.42) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512594-A | ADMINISTERING TO TREAT A MEDICAL CONDITION MEDIATED BY ONE OR MORE LEUKOTRIENES | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |