SCHEMBL8979786

SCHEMBL8979786

CCN(c1cccc(S(N)(=O)=O)n1)S(C)(=O)=O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
HSD17B10 Q99714 1/20 0.35
CA1 P00915 5/20 0.34
CA2 P00918 5/20 0.34
CA9 Q16790 5/20 0.34
CA12 O43570 3/20 0.34
MAPT P10636 1/20 0.33
LOX P28300 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
CYP2C8 P10632 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C18 P33260 1/20 0.30
CDK1 P06493 1/20 0.30
MTOR P42345 1/20 0.30
SMG1 Q96Q15 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979908 0.88 MAPT (0.33) CA1CA2CA9CA12MAPT
SCHEMBL8979853 0.84 MAPT (0.31) MAPT
SCHEMBL8979849 0.82 MAPT (0.30) MAPT
SCHEMBL17258671 0.70 ALDH1A1 (0.69) ALDH1A1HSD17B10
SCHEMBL8979765 0.69 ALDH1A1 (0.44) ALDH1A1MAPT
SCHEMBL3465074 0.67 CA2 (0.32) CA1CA2CA9CA12LOX
SCHEMBL6449500 0.66 SLC40A1 (0.47) ALDH1A1HSD17B10CA1CA2CA9
SCHEMBL22163630 0.66 CA12 (0.38) ALDH1A1CA1CA2CA9CA12
SCHEMBL22169026 0.65 CA2 (0.38) CA1CA2CA9CA12
SCHEMBL3466764 0.65 IRAK4 (0.34) CA1CA2CA9CA12LOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5583231-A HERBICIDE ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-12-10 US disclosed
US-5457084-A Herbicides use at low dosage ISHIHARA SANGYO KAISHA LTD. (JP) 1995-10-10 US disclosed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
EP-0496608-A1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-07-29 EP disclosed