Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196705 | 0.88 | CYP19A1 (0.39) | ACHEAGTR1PDE3BPDE3A | |
| SCHEMBL8979828 | 0.84 | ACHE (0.46) | ACHEAGTR1PPARGPDE3BPDE3A | |
| SCHEMBL8801326 | 0.83 | ACHE (0.45) | ACHEAGTR1PPARGAGTR2 | |
| SCHEMBL8979747 | 0.82 | BRS3 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8979757 | 0.79 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8979781 | 0.79 | AGTR1 (0.48) | ACHEAGTR1AGTR2 | |
| SCHEMBL1888778 | 0.79 | PPARG (0.44) | ACHEAGTR1PPARGPDE3BPDE3A | |
| SCHEMBL8979771 | 0.76 | BRS3 (0.49) | AGTR1PPARGAGTR2 | |
| SCHEMBL1892431 | 0.76 | ACHE (0.46) | ACHEAGTR1PPARG | |
| SCHEMBL8801432 | 0.75 | ACHE (0.39) | ACHEAGTR1PPARGAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565464-A | Compounds having angiotensine II antagonistic activity | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1996-10-15 | — | — | US | disclosed |
| WO-1993003018-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1993-02-18 | — | — | WO | disclosed |