Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979813 | 0.88 | ACHE (0.46) | PDE3BPDE3AACHEAGTR1 | |
| SCHEMBL9196708 | 0.84 | CYP19A1 (0.41) | CYP19A1PDE3BPDE3AACHEAGTR1 | |
| SCHEMBL9205134 | 0.83 | ACHE (0.38) | CYP19A1PDE3BPDE3AACHEAGTR1 | |
| SCHEMBL27863097 | 0.78 | ALDH1A1 (0.39) | CYP19A1PDE3BPDE3AACHEAGTR1 | |
| SCHEMBL8979747 | 0.76 | BRS3 (0.54) | AGTR1BRS3 | |
| SCHEMBL27771400 | 0.76 | KDM4E (0.41) | CYP19A1PDE3BPDE3AACHEKDM4E | |
| SCHEMBL2692033 | 0.76 | CYP19A1 (0.50) | CYP19A1ACHEKDM4EGALR3ALDH1A1 | |
| SCHEMBL9274128 | 0.75 | SMN1; SMN2 (0.36) | ACHEWNT3AAGTR1GAABRS3 | |
| SCHEMBL9205143 | 0.75 | CYP19A1 (0.39) | CYP19A1PDE3BPDE3AACHEKDM4E | |
| SCHEMBL28781819 | 0.75 | CYP19A1 (0.39) | CYP19A1PDE3BPDE3AACHEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641329-A1 | COMPOUNDS HAVING ANGIOTENSINE II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1995-03-08 | — | — | EP | disclosed |