Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841625 | 0.85 | LMNA (0.54) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL2983828 | 0.85 | HSD11B1 (0.54) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL7071544 | 0.81 | LMNA (0.52) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL10179507 | 0.80 | LMNA (0.49) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL3844211 | 0.78 | LMNA (0.50) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL3843866 | 0.78 | LMNA (0.50) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL941645 | 0.77 | LMNA (0.57) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL8581403 | 0.76 | LMNA (0.48) | LMNAMAPK1HSD11B1HSD17B3MEN1 | |
| SCHEMBL1200310 | 0.76 | ALDH1A1 (0.76) | LMNAMAPK1MEN1KMT2AGAA | |
| SCHEMBL29586241 | 0.75 | LMNA (0.59) | LMNAMAPK1HSD11B1HSD17B3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706419-A1 | INTERFACIAL POLYMERIZATION IN A POROUS SUBSTRATE AND SUBSTRATES FUNCTIONALIZED WITH PHOTOCHEMICAL GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001219-A1 | INTERFACIAL POLYMERIZATION IN A POROUS SUBSTRATE AND SUBSTRATES FUNCTIONALIZED WITH PHOTOCHEMICAL GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-12 | — | — | WO | disclosed |