Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138864 | 0.82 | RXFP1 (0.58) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL9385776 | 0.82 | TP53 (0.45) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL367269 | 0.80 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL10743435 | 0.79 | TTR (0.44) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL10750161 | 0.76 | RAB9A (0.40) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL6143924 | 0.76 | ABCC4 (0.44) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL10744297 | 0.74 | PTGS2 (0.45) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| Acetic Acid SCHEMBL6142954 | 0.74 | ALDH1A1 (0.48) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL9389636 | 0.73 | RXFP1 (0.45) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL9390809 | 0.73 | RXFP1 (0.55) | RAB9ASMN1; SMN2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571822-A | AMINO-2-PHENYL-4-QUINOLONE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996010563-A1 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-04-11 | — | — | WO | disclosed |