Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869301 | 0.81 | CA12 (0.50) | ALDH1A1KMOKDM4ETSHRCA2 | |
| SCHEMBL9035708 | 0.81 | CES2 (0.55) | NPC1LMNAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL11756446 | 0.81 | TP53 (0.56) | NPC1KMOKDM4EMAPTRAB9A | |
| SCHEMBL3863357 | 0.80 | LOXL2 (0.51) | ALDH1A1NPC1KMOMEN1RAB9A | |
| SCHEMBL339923 | 0.79 | ERCC5 (0.58) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL1277041 | 0.79 | PARP1 (0.50) | NPC1LMNAPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL5619554 | 0.79 | PARP1 (0.50) | ALDH1A1NPC1MAPTMEN1RAB9A | |
| SCHEMBL28415551 | 0.79 | CES2 (0.66) | ALDH1A1MITFLMNAKMOKDM4E | |
| Hydrochloric Acid SCHEMBL1277032 | 0.79 | LOXL2 (0.50) | ALDH1A1NPC1KMOMEN1RAB9A | |
| SCHEMBL26966709 | 0.78 | KMT2A (0.44) | ALDH1A1NPC1LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571822-A | AMINO-2-PHENYL-4-QUINOLONE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996010563-A1 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-04-11 | — | — | WO | disclosed |